The Center of Regenerative Medicine (CRM) is a multidisciplinary group of scientists focused on advancing regenerative medicine through excellence in education and collaborate research. The center strives to facilitate and enhance research in regenerative medicine at the university, as well as to educate the public on the vast potential that regenerative medicine holds for human health. Ultimately, the center aims to conduct research grounded in basic biology that will lead to transformations in patient care.
The hCTO Core of the CRM provides facilities, reagents and resources for stem cell use, data collection and training.
The Bioinformatics Research Core of the CRM provides experimental design, data analysis, and custom pipelines for many types of data, including ChIP-seq, RNA seq, ATAC-seq, FAIRE-seq, microarray, and whole genome sequencing, among others.
The Elvie L. Taylor Histology Core Facility provides full technical services for histology and morphological investigations. This facility supports experimental biology throughout the Washington University research community.
The Developmental Biology Microscopy Core has a Laser Capture Microdissection Microscope.
Washington University is home to one of the largest zebrafish facilities in the world. And with robotic feeding and cleaning systems, it is the world’s most modern.
Other university cores and centers
CHPC provides access to high performance computing resources, a broad spectrum of scientific computing software, and expert support to help faculty make use of deep computing resources. Usage is free to all faculty of Washington University.
Every movement, every thought and every heartbeat is the response to electrical signals in our tissues. Defects in these electrical signals underlie multiple diseases, including cardiac arrhythmias, epilepsies and other neurological disorders, muscle disorders, as well as diabetes, cystic fibrosis, and kidney disorders, involving organs not typically thought of as being electrically excitable. Reflecting increased awareness of the role of electrical excitability and the myriad diseases now linked directly to derangements in membrane excitability, CIMED pulls together scientists from different disciplines with a fundamental interest in excitability diseases. CIMED investigators are uniquely positioned to provide fundamental insights into membrane excitability disease mechanisms, and work to develop novel therapeutics.
The mission of the Diabetes Research Center (DRC) is to support and enhance research in diabetes and related metabolic diseases through expert biomedical research cores, a vibrant pilot and feasibility program and a dynamic enrichment program, all of which address the evolving needs of diabetes investigators.
The Flow Cytometry Core provides investigators with instrumentation and support for cell sorting, as well as acquisition and analysis of flow cytometry data.
The Genome Technology Access Center (GTAC) provides DNA/RNA analysis resources for researchers at Washington University and beyond. GTAC currently provides NextGen sequencing (Illumina HiSeqs), microarrays (all formats) and quantitative PCR.
This core enables small molecule screens to identify agonists/antagonists of biologically/pathologically interesting proteins and perform sub- or genome-wide siRNA screens in live cell functional assays.
The mission of the Hope Center is to improve the lives of people living with neurological disorders, through discovery of fundamental mechanisms of neurodegeneration that translate new findings into cures and treatments. The Hope Center brings together world-class scientists and clinician scientists whose expertise spans many different disciplines and diseases. Their common focus is neurodegeneration, which occurs when brain cells (“neurons”) and their connections (“synapses”) are damaged by disease or injury. These investigators share the conviction that there are common molecular mechanisms of degeneration, and that fundamental discoveries related to one disease can lead to cures and treatments in others.
The Hope Center Animal Surgery Core provides technical support and conducts experiments employing rodent models of neurological diseases.
The Hope Center Viral Vectors core provides lentiviral and AAV viral vectors for research applications. The Core provides training and advice on vector usage and design and both small and large scale vector preparations.
The mission of the Mouse Genetics Core (MGC) is to provide a cost-effective method for generating and maintaining genetically altered mice for the entire Washington University research community.
Behind every advance in cancer prevention, diagnosis and treatment is a history of painstaking research. The Siteman Cancer Center has expertise in every step of the research process.
The Tissue Culture Support Center maintains a stockroom offering approximately 1500 commonly used lab consumables from more than 20 vendors, which are available to the research community at a discount. Same day pickup or delivery is available for most products. The center also provides basic tissue culture services and training in stem cell technology. They offer long-term cell storage, mycoplasma testing and provide access to various technologies requiring specialized equipment such as Amaxa’s 4D Nucleofection device and Seahorse Bioscience’s XF technology.