Current research
Our research is highly diverse and includes topics ranging from embryogenesis, cell reprogramming and organogenesis to aging and stem cell engineering.
Our ongoing and future work will focus on new and emerging areas of developmental biology, such as epigenetics and genomics.
Model systems
We house one of the largest zebrafish facilities in the world. Along with zebrafish (D. rerio), we study several other model systems, including the fruit fly (D. melanogaster), nematode (C. elegans) and mouse (M. musculus), as well as tissue culture systems and embryonic stem cells.
Latest news
Dr. Nerbonne’s New Publication
Congratulations to Dr. Nerbonne’s Lab on their recent publication! Modulation of the effects of Class-Ib antiarrhythmics on cardiac NaV1.5-encoded channels by accessory NaVβ subunits. Zhu W, Wang W, Angsutararux P, Mellor RL, Isom LL, Nerbonne JM, Silva JR. JCI Insight. 2021 Jun 22:143092.
Dr. Ornitz’s New Publication
Congratulations to Dr. David Ornitz’s Lab on their recent publication! Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments. Leek CC, Soulas JM, Bhattacharya I, Ganji E, Locke RC, Smith MC, Bhavsar JD, Polson SW, Ornitz DM, Killian ML. Dev Dyn. 2021 Jun […]
Dr. Theunissen’s New Publication
Congratulations to Dr. Theunissen’s Lab on their recent publication! Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening. Khan SA, Park KM, Fischer LA, Dong C, Lungjangwa T, Jimenez M, Casalena D, Chew B, Dietmann S, Auld DS, Jaenisch R, Theunissen TW. Cell Rep. 2021 Jun 15;35(11):109233.