Current research
Our research is highly diverse and includes topics ranging from embryogenesis, cell reprogramming and organogenesis to aging and stem cell engineering.
Our ongoing and future work will focus on new and emerging areas of developmental biology, such as epigenetics and genomics.
Model systems
We house one of the largest zebrafish facilities in the world. Along with zebrafish (D. rerio), we study several other model systems, including the fruit fly (D. melanogaster), nematode (C. elegans) and mouse (M. musculus), as well as tissue culture systems and embryonic stem cells.
Latest news
Dr. Johnson’s New Publication
Congratulations to Dr. Aaron Johnson’s Lab on their recent publication! A pathogenic mechanism associated with myopathies and structural birth defects involves TPM2-directed myogenesis. McAdow J, Yang S, Ou T, Huang G, Dobbs MB, Gurnett CA, Greenberg MJ, Johnson AN. JCI Insight. 2022 Jun 22;7(12):e152466.
Dr. Ornitz’s New Publication
Congratulations to Dr. David Ornitz’s Lab on their recent publication! Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis. Hiller BE, Yin Y, Perng YC, de Araujo Castro Í, Fox LE, Locke MC, Monte KJ, López CB, Ornitz DM, Lenschow DJ. PLoS Pathog. 2022 […]
Dr. Yoo’s New Publication
Congratulations to Dr. Andrew Yoo’s Lab on their recent publication! Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons. Capano LS, Sato C, Ficulle E, Yu A, Horie K, Kwon JS, Burbach KF, Barthélemy NR, Fox SG, Karch CM, Bateman RJ, Houlden H, Morimoto RI, Holtzman DM, Duff […]