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A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. Dong C, Fu S, Karvas RM, Chew B, Fischer LA, Xing X, Harrison JK, Popli P, Kommagani R, Wang T, Zhang B, Theunissen TW. Nat Commun. 2022 May 10;13(1):2548.

Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens. Karvas RM, Khan SA, Verma S, Yin Y, Kulkarni D, Dong C, Park KM, Chew B, Sane E, Fischer LA, Kumar D, Ma L, Boon ACM, Dietmann S, Mysorekar IU, Theunissen TW. Cell Stem Cell. 2022 May 5;29(5):810-825.e8.

Further Evidence that Inhibition of Neuronal Voltage-Gated Calcium Channels Contributes to the Hypnotic Effect of Neurosteroid Analogue, 3β-OH. Timic Stamenic T, Manzella FM, Maksimovic S, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Front Pharmacol. 2022 May 23;13:850658.

Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells. Luff SA, Creamer JP, Valsoni S, Dege C, Scarfò R, Dacunto A, Cascione S, Randolph LN, Cavalca E, Merelli I, Morris SA, Ditadi A, Sturgeon CM. Nat Cell Biol. 2022 Apr 28. doi: 10.1038/s41556-022-00898-9.

Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment. Whitson JA, Johnson R, Wang L, Bammler TK, Imai SI, Zhang H, Fredrickson J, Latorre-Esteves E, Bitto A, MacCoss MJ, Rabinovitch PS. Geroscience. 2022 Apr 13. doi: 10.1007/s11357-022-00564-w.

Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition. Weagley JS, Zaydman M, Venkatesh S, Sasaki Y, Damaraju N, Yenkin A, Buchser W, Rodionov DA, Osterman A, Ahmed T, Barratt MJ, DiAntonio A, Milbrandt J, Gordon JI. Cell Rep. 2022 Apr 26;39(4):110738.

Long-Term Effects of Nasoalveolar Molding in Patients With Unilateral Cleft Lip and Palate: A Systematic Review and Meta-Analysis. Padovano WM, Skolnick GB, Naidoo SD, Snyder-Warwick AK, Patel KB. Cleft Palate Craniofac J. 2022 Apr;59(4):462-474.

Short-Duration, Pulsatile, Electrical Stimulation Therapy Accelerates Axon Regeneration and Recovery following Tibial Nerve Injury and Repair in Rats. Roh J, Schellhardt L, Keane GC, Hunter DA, Moore AM, Snyder-Warwick AK, Mackinnon SE, Wood MD. Plast Reconstr Surg. 2022 Apr 1;149(4):681e-690e.

Capybara: A computational tool to measure cell identity and fate transitions. Kong W, Fu YC, Holloway EM, Garipler G, Yang X, Mazzoni EO, Morris SA. Cell Stem Cell. 2022 Apr 7;29(4):635-649.e11

The Enantiomer of Allopregnanolone Prevents Pressure-Mediated Retinal Degeneration Via Autophagy. Ishikawa M, Nakazawa T, Kunikata H, Sato K, Yoshitomi T, Krishnan K, Covey DF, Zorumski CF, Izumi Y. Front Pharmacol. 2022 Mar 16;13:855779.

FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury. Lee B, Oh Y, Cho E, DiAntonio A, Cavalli V, Shin JE, Choi HW, Cho Y.J Biol Chem. 2022 Mar;298(3):101647.

Synthetic neuroactive steroids as new sedatives and anaesthetics: Back to the future. Manzella FM, Covey DF, Jevtovic-Todorovic V, Todorovic SM. J Neuroendocrinol. 2022 Feb;34(2):e13086.

Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN. Li Y, Pazyra-Murphy MF, Avizonis D, de Sá Tavares Russo M, Tang S, Chen CY, Hsueh YP, Bergholz JS, Jiang T, Zhao JJ, Zhu J, Ko KW, Milbrandt J, DiAntonio A, Segal RA. J Cell Biol. 2022 Feb 7;221(2):e202106080.

Spatiotemporal expression of regulatory kinases directs the transition from mitosis to cellular morphogenesis in Drosophila. Yang S, McAdow J, Du Y, Trigg J, Taghert PH, Johnson AN. Nat Commun. 2022 Feb 9;13(1):772.

A phytobacterial TIR domain effector manipulates NAD+ to promote virulence. Eastman S, Smith T, Zaydman MA, Kim P, Martinez S, Damaraju N, DiAntonio A, Milbrandt J, Clemente TE, Alfano JR, Guo M. New Phytol. 2022 Jan;233(2):890-904.

IL-4 expressing cells are recruited to nerve after injury and promote regeneration. Pan D, Schellhardt L, Acevedo-Cintron JA, Hunter D, Snyder-Warwick AK, Mackinnon SE, Wood MD. Exp Neurol. 2022 Jan;347:113909.

Protein phosphatase 2A restrains DLK signaling to promote proper Drosophila synaptic development and mammalian cortical neuron survival. Hayne M, DiAntonio A. Hayne M, DiAntonio A. Neurobiol Dis. 2022 Feb;163:105586.

Intrinsic mechanisms in the gating of resurgent Na+ currents. Ransdell JL, Moreno JD PhD, Bhagavan D, Silva JR, Nerbonne JM. Elife. 2022 Jan 25;11:e70173.

Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients. Bloom AJ, Mao X, Strickland A, Sasaki Y, Milbrandt J, DiAntonio A.
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Generating Trophoblast Stem Cells from Human Naïve Pluripotent Stem Cells. Dong C, Theunissen TW. Methods Mol Biol. 2022;2416:91-104.

Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients. Bloom AJ, Mao X, Strickland A, Sasaki Y, Milbrandt J, DiAntonio A.
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Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites. Dietzen NM, Arcario MJ, Chen LJ, Petroff JT 2nd, Moreland KT, Krishnan K, Brannigan G, Covey DF, Cheng WW. Elife. 2022 Jan 4;11:e74306.