- Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington’s disease neurodegeneration. Lee SW, Oh YM, Victor MB, Yang Y, Chen S, Strunilin I, Dahiya S, Dolle RE, Pak SC, Silverman GA, Perlmutter DH, Yoo AS. Nat Aging. 2023 Dec 8. PMID: 38066314
- Signaling mechanisms that direct cell fate specification and morphogenesis in human embryonic stem cells-based models of human gastrulation. Stringa B, Solnica-Krezel L. Emerg Top Life Sci. 2023 Dec 18;7(4):383-396. PMID: 38087898
- Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications. Qian M, Xu Y, Covey DF. RSC Adv. 2023 Dec 14;13(51):36484-36492. PMID: 3809925
- Cardiac radiation improves ventricular function in mice and humans with cardiomyopathy. Pedersen LN, Valenzuela Ripoll C, Ozcan M, Guo Z, Lotfinaghsh A, Zhang S, Ng S, Weinheimer C, Nigro J, Kovacs A, Diab A, Klaas A, Grogan F, Cho Y, Ataran A, Luehmann H, Heck A, Kolb K, Strong L, Navara R, Walls GM, Hugo G, Samson P, Cooper D, Reynoso FJ, Schwarz JK, Moore K, Lavine K, Rentschler SL, Liu Y, Woodard PK, Robinson C, Cuculich PS, Bergom C, Javaheri A. Med. 2023 Nov 21:S2666-6340(23)00337-9. PMID: 38029754
- UNC-49 is a redox-sensitive GABAA receptor that regulates the mitochondrial unfolded protein response cell nonautonomously. Pohl F, Germann AL, Mao J, Hou S, Bakare B, Kong Thoo Lin P, Yates K, Nonet ML, Akk G, Kornfeld K, Held JM. Sci Adv. 2023 Nov 3;9(44):eadh2584. Epub 2023 Nov 1.PMID: 37910615
- Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism. Leid J, Gray R, Rakita P, Koenig AL, Tripathy R, Fitzpatrick JAJ, Kaufman C, Solnica-Krezel L, Lavine KJ. Biol Open. 2023 Jul 15;12(7):bio059905. PMID: 37746814
- The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations. Klontz E, Obi JO, Wang Y, Glendening G, Carr J, Tsibouris C, Buddula S, Nallar S, Soares AS, Beckett D, Redzic JS, Eisenmesser E, Palm C, Schmidt K, Scudder AH, Obiorah T, Essuman K, Milbrandt J, Diantonio A, Ray K, Snyder MLD, Deredge D, Snyder GA. J Biol Chem. 2023 Sep 25:105290. PMID: 37758001
- Natamycin interferes with ergosterol-dependent lipid phases in model membranes. Akkerman V, Scheidt HA, Reinholdt P, Bashawat M, Szomek M, Lehmann M, Wessig P, Covey DF, Kongsted J, Müller P, Wüstner D. BBA Adv. 2023 Aug 25;4:100102. PMID: 37691996
- Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes. Jindal K, Adil MT, Yamaguchi N, Yang X, Wang HC, Kamimoto K, Rivera-Gonzalez GC, Morris SA. Nat Biotechnol. 2023 Sep 25. PMID: 37749269
- Spinal Cord Injury and Assays for Regeneration. Burris B, Mokalled MH. Methods Mol Biol. 2024;2707:215-222. PMID: 37668915
- Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2). Bodmer NK, Knutsen RH, Roth RA, Castile RM, Brodt MD, Gierasch CM, Broekelmann TJ, Gibson MA, Haspel JA, Lake SP, Koenitzer JR, Brody SL, Silva MJ, Mecham RP, Ornitz DM. Dev Dyn. 2023 Sep 9. PMID: 37688792
- 3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages. Karvas, R.M., Zemke, J.E., Ali, S.S., Sane, S., Dong, C., Fischer, L.A., Park, K., Upton, E., Wang, F., Park, K., Hao, S., Chew, B., Meyer, B., Zhou, C., Dietmann, S., and T.W. Theunissen (2023). Cell Stem Cell, 30, 1148-1165.
- VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway. Lee C, Chen R, Sun G, Liu X, Lin X, He C, Xing L, Liu L, Jensen LD, Kumar A, Langer HF, Ren X, Zhang J, Huang L, Yin X, Kim J, Zhu J, Huang G, Li J, Lu W, Chen W, Liu J, Hu J, Sun Q, Lu W, Fang L, Wang S, Kuang H, Zhang Y, Tian G, Mi J, Kang BA, Narazaki M, Prodeus A, Schoonjans L, Ornitz DM, Gariepy J, Eelen G, Dewerchin M, Yang Y, Ou JS, Mora A, Yao J, Zhao C, Liu Y, Carmeliet P, Cao Y, Li X. Signal Transduct Target Ther. 2023 Aug 18;8(1):305. PMID: 37591843
- SOX9 Governs Gastric Mucous Neck Cell Identity and Is Required for Injury-Induced Metaplasia. Willet SG, Thanintorn N, McNeill H, Huh SH, Ornitz DM, Huh WJ, Hoft SG, DiPaolo RJ, Mills JC. Cell Mol Gastroenterol Hepatol. 2023;16(3):325-339. PMID: 37270061
- Defining cardiac functional recovery in end-stage heart failure at single-cell resolution. Amrute JM, Lai L, Ma P, Koenig AL, Kamimoto K, Bredemeyer A, Shankar TS, Kuppe C, Kadyrov FF, Schulte LJ, Stoutenburg D, Kopecky BJ, Navankasattusas S, Visker J, Morris SA, Kramann R, Leuschner F, Mann DL, Drakos SG, Lavine KJ. Nat Cardiovasc Res. 2023 Apr;2(4):399-416. PMID: 37583573
- Modeling X-chromosome inactivation and reactivation during human development. Khan SA, Theunissen TW. Curr Opin Genet Dev. 2023 Aug 17;82:102096. PMID: 37597506
- Functional trajectories during innate spinal cord repair. Jensen NO, Burris B, Zhou L, Yamada H, Reyes C, Pincus Z, Mokalled MH. Front Mol Neurosci. 2023 Jul 10;16:1155754. PMID: 37492522
- Kv12-encoded K+ channels drive the day-night switch in the repetitive firing rates of SCN neurons. Hermanstyne TO, Yang ND, Granados-Fuentes D, Li X, Mellor RL, Jegla T, Herzog ED, Nerbonne JM. J Gen Physiol. 2023 Sep 4;155(9):e202213310. PMID: 37516908
- Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse Lesage A, Lorenzini M, Burel S, Sarlandie M, Bibault F, Lindskog C, Maloney D, Silva JR, Townsend RR, Nerbonne JM, Marionneau C. J Gen Physiol. 2023 Sep 4;155(9):e202213293. PMID: 3751691
- Modeling Huntington disease through microRNA-mediated neuronal reprogramming identifies age-associated autophagy dysfunction driving the onset of neurodegeneration. Oh YM, Lee SW, Yoo AS. Autophagy. 2023 Sep;19(9):2613-2615. PMID: 36727408
- SOX9 Governs Gastric Mucous Neck Cell Identity and Is Required for Injury-Induced Metaplasia. Willet SG, Thanintorn N, McNeill H, Huh SH, Ornitz DM, Huh WJ, Hoft SG, DiPaolo RJ, Mills JC. Cell Mol Gastroenterol Hepatol. 2023 Jun 1:S2352-345X(23)00106-6. PMID: 37270061
- Effects of NALCN-Encoded Na+ Leak Currents on the Repetitive Firing Properties of SCN Neurons Depend on K+-Driven Rhythmic Changes in Input Resistance. Yang ND, Mellor RL, Hermanstyne TO, Nerbonne JM. J Neurosci. 2023 Jul 12;43(28):5132-5141. PMID: 37339878
- Progenitor-derived glia are required for spinal cord regeneration in zebrafish. Zhou L, McAdow AR, Yamada H, Burris B, Klatt Shaw D, Oonk K, Poss KD, Mokalled MH. Development. 2023 May 15;150(10):dev201162. PMID: 37213080
- Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death. Wernlé KK, Sonnenfelt MA, Leek CC, Ganji E, Sullivan AL, Offutt C, Shuff J, Ornitz DM, Killian ML. Dev Dyn. 2023 May 22. PMID: 37212424
- Neonatal exposure to a neuroactive steroid alters low-frequency oscillations in the subiculum. Fine-Raquet B, Manzella FM, Joksimovic SM, Dietz RM, Orfila JE, Sampath D, Tesic V, Atluri N, Covey DF, Raol YH, Jevtovic-Todorovic V, Herson PS, Todorovic SM. Exp Biol Med (Maywood) 2023 Apr;248(7):578-587. PMID: 37309730
- Characterization of a robust mouse model of heart failure with preserved ejection fraction. Matsiukevich D, Kovacs A, Li T, Kokkonen-Simon K, Matkovich SJ, Oladipupo SS, Ornitz DM. Am J Physiol Heart Circ Physiol. 2023 Aug 1;325(2):H203-H231. PMID: 37204871
- Sleep-wake patterns are altered with age, Prdm13 signaling in the DMH, and diet restriction in mice. Tsuji S, Brace CS, Yao R, Tanie Y, Tada H, Rensing N, Mizuno S, Almunia J, Kong Y, Nakamura K, Furukawa T, Ogiso N, Toyokuni S, Takahashi S, Wong M, Imai SI, Satoh. Life Sci Alliance. 2023 Apr 12;6(6):e202301992. PMID: 37045472
- Peptidoglycan recognition in Drosophila is mediated by LysMD3/4. Snee M, Wever J, Guyton J, Beehler-Evans R, Yokoyama CC, Micchelli CA. J Biol Chem. 2023 Apr 26:104758. PMID: 37116706
- Whole-brain imaging of freely-moving zebrafish. Hasani H, Sun J, Zhu SI, Rong Q, Willomitzer F, Amor R, McConnell G, Cossairt O, Goodhill GJ. Front Neurosci. 2023 Apr 17;17:1127574. PMID: 37139528
- Fat and Dachsous cadherins in mammalian development. Kasiah J, McNeill H. Curr Top Dev Biol. 2023;154:223-244. PMID: 37100519
- Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway. Fulford AD, Enderle L, Rusch J, Hodzic D, Holder MV, Earl A, Oh RH, Tapon N, McNeill H. J Cell Biol. 2023 May 1;222(5):e202204059. PMID: 37071483 Free PMC article.
- Duplication Versus Deletion Through the Lens of 15q13.3: Clinical and Research Implications of Studying Copy Number Variants Associated with Neuropsychiatric Disorders in Induced Pluripotent Stem Cell-Derived Neurons. Antony I, Narasimhan M, Shen R, Prakasam R, Kaushik K, Chapman G, Kroll KL. Stem Cell Rev Rep. 2023 Apr;19(3):639-650. PMID: 36370261 Review.
- Neurosteroid enantiomers as potentially novel neurotherapeutics. Covey DF, Evers AS, Izumi Y, Maguire JL, Mennerick SJ, Zorumski CF. Neurosci Biobehav Rev. 2023 Apr 20;149:105191. PMID: 37085023 Review
- Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia. Patzek S, Liu Z, de la O S, Chang S, Byrnes LE, Zhang X, Ornitz DM, Sneddon JB. iScience. 2023 Mar 25;26(4):106500. PMID: 37096042 Free PMC article.
- Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors. Angsutararux P, Dutta AK, Marras M, Abella C, Mellor RL, Shi J, Nerbonne JM, Silva JR. J Gen Physiol. 2023 May 1;155(5):e202213300. PMID: 36944081
- Dissecting cell identity via network inference and in silico gene perturbation. Kamimoto K, Stringa B, Hoffmann CM, Jindal K, Solnica-Krezel L, Morris SA. Nature. 2023 Feb;614(7949):742-751. PMID: 36755098 Free PMC article.
- The Mechanism of Enantioselective Neurosteroid Actions on GABAA Receptors. Tateiwa H, Chintala SM, Chen Z, Wang L, Amtashar F, Bracamontes J, Germann AL, Pierce SR, Covey DF, Akk G, Evers AS. Biomolecules. 2023 Feb 9;13(2):341. PMID: 36830708 Free PMC article