Congratulations to Dr. Covey’s Lab on their recent publication! GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter JF, Dror RO, […]
Congratulations to Thor Theunissen’s Lab on their recent publication! Self-renewing human naïve pluripotent stem cells dedifferentiate in 3D culture and form blastoids spontaneously Guo M, Wu J, Chen C, Wang X, Gong A, Guan W, Karvas RM, Wang K, Min M, Wang Y, Theunissen TW, Gao S, Silva JCR. Nat Commun. 2024 Jan 22;15(1):668. PMID: 38253551
Congratulations to Dr. Covey’s Lab on their recent publication! Neuroactive steroid effects on autophagy in a human embryonic kidney 293 (HEK) cell model Salvatore SV, Ilagan MXG, Shu H, Lambert PM, Benz A, Qian M, Covey DF, Zorumski CF, Mennerick S. Sci Rep. 2024 Jan 10;14(1):1042. PMID: 38200205
Congratulations to Dr. Imai’s Lab on their recent publication! Absolute quantification of nicotinamide mononucleotide in biological samples by double isotope-mediated liquid chromatography-tandem mass spectrometry (dimeLC-MS/MS) Unno J, Mills KF, Ogura T, Nishimura M, Imai SI. NPJ Aging. 2024 Jan 2;10(1):2. PMID: 38167419
Congratulations to Dr. DiAntonio’s Lab on their recent publication! Sarm1 knockout prevents type 1 diabetic bone disease in females independent of neuropathy Brazill JM, Shen IR, Craft CS, Magee KL, Park JS, Lorenz M, Strickland A, Wee NK, Zhang X, Beeve AT, Meyer GA, Milbrandt J, DiAntonio A, Scheller EL. JCI Insight. 2024 Jan 4:e175159. PMID: 38175722
Congratulations to Dr. Covey’s Lab on their recent publication! 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis Freitas FP, Alborzinia H, Dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, Inague A, Klein C, Aroua N, Kaushal K, Kast B, Lorenz SM, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Atici S, Doll SG, […]
Congratulations to Dr. Kornfeld’s Lab on their recent publication! The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging Egan BM, Pohl F, Anderson X, Williams SC, Adodo IG, Hunt P, Wang Z, Chiu CH, Scharf A, Mosley M, Kumar S, Schneider DL, Fujiwara H, Hsu FF, Kornfeld K. Development. 2024 Jan 29:dev.202146. PMID: 3828454
Congratulations to Dr. Imai’s Lab on their recent publication! DMHPpp1r17 neurons regulate aging and lifespan in mice through hypothalamic-adipose inter-tissue communication Tokizane K, Brace CS, Imai SI. Cell Metab. 2024 Jan 1:S1550-4131(23)00462-X. PMID: 38194970
Congratulations to Dr. Yoo’s Lab on their recent publication! Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington’s disease neurodegeneration Lee SW, Oh YM, Victor MB, Yang Y, Chen S, Strunilin I, Dahiya S, Dolle RE, Pak SC, Silverman GA, Perlmutter DH, Yoo AS. Nat Aging. 2023 Dec 8. PMID: 38066314
Congratulations to Dr. Solnica-Krezel’s Lab on their recent publication! Signaling mechanisms that direct cell fate specification and morphogenesis in human embryonic stem cells-based models of human gastrulation Stringa B, Solnica-Krezel L. Emerg Top Life Sci. 2023 Dec 18;7(4):383-396. PMID: 38087898