Congratulations to Douglas Covey’s Lab on their recent publication!
Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid. Manzella FM, Cabrera OH, Wilkey D, Fine-Raquet B, Klawitter J, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Br J Anaesth. 2023 Feb;130(2):154-164. doi: 10.1016/j.bja.2022.09.025. Epub 2022 Nov 22. PMID: 36428160