Congratulations to Dr. Covey’s Lab on their recent publication! 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis Freitas FP, Alborzinia H, Dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, Inague A, Klein C, Aroua N, Kaushal K, Kast B, Lorenz SM, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Atici S, Doll SG, […]
Congratulations to Dr. Kornfeld’s Lab on their recent publication! The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging Egan BM, Pohl F, Anderson X, Williams SC, Adodo IG, Hunt P, Wang Z, Chiu CH, Scharf A, Mosley M, Kumar S, Schneider DL, Fujiwara H, Hsu FF, Kornfeld K. Development. 2024 Jan 29:dev.202146. PMID: 3828454
Congratulations to Dr. Imai’s Lab on their recent publication! DMHPpp1r17 neurons regulate aging and lifespan in mice through hypothalamic-adipose inter-tissue communication Tokizane K, Brace CS, Imai SI. Cell Metab. 2024 Jan 1:S1550-4131(23)00462-X. PMID: 38194970
Congratulations to Dr. Yoo’s Lab on their recent publication! Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington’s disease neurodegeneration Lee SW, Oh YM, Victor MB, Yang Y, Chen S, Strunilin I, Dahiya S, Dolle RE, Pak SC, Silverman GA, Perlmutter DH, Yoo AS. Nat Aging. 2023 Dec 8. PMID: 38066314
Congratulations to Dr. Solnica-Krezel’s Lab on their recent publication! Signaling mechanisms that direct cell fate specification and morphogenesis in human embryonic stem cells-based models of human gastrulation Stringa B, Solnica-Krezel L. Emerg Top Life Sci. 2023 Dec 18;7(4):383-396. PMID: 38087898
Congratulations to Dr. Covey’s Lab on their recent publication! Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications Qian M, Xu Y, Covey DF. RSC Adv. 2023 Dec 14;13(51):36484-36492. PMID: 38099258
Congratulations to Dr. Rentschler’s Lab on their recent publication! Cardiac radiation improves ventricular function in mice and humans with cardiomyopathy Pedersen LN, Valenzuela Ripoll C, Ozcan M, Guo Z, Lotfinaghsh A, Zhang S, Ng S, Weinheimer C, Nigro J, Kovacs A, Diab A, Klaas A, Grogan F, Cho Y, Ataran A, Luehmann H, Heck A, […]
Congratulations to Dr. Kornfeld’s Lab on their recent publication! UNC-49 is a redox-sensitive GABAA receptor that regulates the mitochondrial unfolded protein response cell nonautonomously Pohl F, Germann AL, Mao J, Hou S, Bakare B, Kong Thoo Lin P, Yates K, Nonet ML, Akk G, Kornfeld K, Held JM. Sci Adv. 2023 Nov 3;9(44):eadh2584. Epub 2023 Nov […]
Congratulations to Dr. Solnica-Krezel’s Lab on their recent publication! Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism Leid J, Gray R, Rakita P, Koenig AL, Tripathy R, Fitzpatrick JAJ, Kaufman C, Solnica-Krezel L, Lavine KJ. Biol Open. 2023 Jul 15;12(7):bio059905. PMID: 37746814
Congratulations to Dr. DiAntonio’s Lab on their recent publication! The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations Klontz E, Obi JO, Wang Y, Glendening G, Carr J, Tsibouris C, Buddula S, Nallar S, Soares AS, Beckett D, Redzic JS, Eisenmesser E, Palm C, Schmidt K, Scudder AH, Obiorah T, […]