Congratulations to Aaron Johnson, PhD., Associate Professor in the Department of Developmental Biology and his lab on their research on the effects of brain inflammation on muscle function!
From the article publish by the Washington University School of Medicine:
“The study pinpoints potential targets for preventing or treating muscle weakness related to brain inflammation. The researchers found that IL-6 activates what is called the JAK-STAT pathway in muscle, and this is what causes the reduced energy production of mitochondria. Several therapeutics already approved by the Food and Drug Administration for other diseases can block this pathway. JAK inhibitors as well as several monoclonal antibodies against IL-6 are approved to treat various types of arthritis and manage other inflammatory conditions.”
Read the full article at: Brain inflammation triggers muscle weakness after infections – Washington University School of Medicine in St. Louis (wustl.edu)